Single-chain antibody-mediated gene delivery into ErbB2-positive human breast cancer cells
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چکیده
منابع مشابه
Anti-CD166 single chain antibody-mediated intracellular delivery of liposomal drugs to prostate cancer cells.
Targeted delivery of small-molecule drugs has the potential to enhance selective killing of tumor cells. We have identified previously an internalizing single chain [single chain variable fragment (scFv)] antibody that targets prostate cancer cells and identified the target antigen as CD166. We report here the development of immunoliposomes using this anti-CD166 scFv (H3). We studied the effect...
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ژورنال
عنوان ژورنال: Cancer Gene Therapy
سال: 2001
ISSN: 0929-1903,1476-5500
DOI: 10.1038/sj.cgt.7700337